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Comparison of virucidal activity of alcohol-based hand sanitizers versus antimicrobial hand soaps in vitro and in vivo


Three ethanol-based sanitisers were compared with three antimicrobial liquid soaps for their efficacy to inactivate polio-, adeno-, vaccinia- and bovine viral diarrhoea virus (BVDV) as well as feline calicivirus (FCV) and murine norovirus (MNV) as surrogates for human norovirus in a suspension test. Additionally, sanitisers and soaps were examined against MNV in a modified fingerpad method. All sanitisers sufficiently inactivated the test viruses in the suspension test whereas two soaps were active only against vaccinia virus and BVDV. In the modified fingerpad test a povidone-iodine-containing soap was superior to the sanitisers whereas the other two soaps showed no activity.

Author: Steinmann J, Paulmann D, Becker B, Bischoff B, Steinmann E

Citation: J Hosp Infect. 2012 Dec;82(4):277-80. doi: 10.1016/j.jhin.2012.08.005. Epub 2012 Sep 23.

Published: 23/09/2012

Publication Type: Journal article

Publisher: Journal of Hospital Infection